Ontology highlight
ABSTRACT:
SUBMITTER: Patel B
PROVIDER: S-EPMC6086787 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Patel Bonny B Parets Sasha S Akana Matthew M Kellogg Gregory G Jansen Michael M Chang Chihyu C Cai Ying Y Fox Rebecca R Niknazar Mohammad M Shraga Roman R Hunter Colby C Pollock Andrew A Wisotzkey Robert R Jaremko Malgorzata M Bisignano Alex A Puig Oscar O
Journal of assisted reproduction and genetics 20180519 8
<h4>Purpose</h4>To develop a comprehensive genetic test for female and male infertility in support of medical decisions during assisted reproductive technology (ART) protocols.<h4>Methods</h4>We developed a next-generation sequencing (NGS) gene panel consisting of 87 genes including promoters, 5' and 3' untranslated regions, exons, and selected introns. In addition, sex chromosome aneuploidies and Y chromosome microdeletions were analyzed concomitantly using the same panel.<h4>Results</h4>The NG ...[more]