Tracking leading anti-Candida compounds in plant samples; Plumbago europaea.

ABSTRACT:

Background and objectives

Due to the importance of finding new and more effective antifungal and antibacterial compounds against invasive vaginitis strains, this study was conducted for fast screening of plant samples.

Materials and methods

Thirty Iranian plant samples were successively extracted by n-hexane, ethyl acetate and methanol to obtain a total of 90 extracts. Each extract was prepared in six concentrations and evaluated for antifungal activity via a micro-broth dilution method. Further phytochemical study of the aerial parts of Plumbago europaea, as the most promising source of anti-Candida compounds (with minimum inhibitory concentration of about 7μg/ml), was carried out and antifungal activity in the ethyl acetate extract was tracked using a

SUBMITTER: Sobhani M 

PROVIDER: S-EPMC6087695 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature