Ontology highlight
ABSTRACT:
SUBMITTER: Picard MAL
PROVIDER: S-EPMC6089595 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Picard Marion A L MAL Cosseau Celine C Ferré Sabrina S Quack Thomas T Grevelding Christoph G CG Couté Yohann Y Vicoso Beatriz B
eLife 20180725
XY systems usually show chromosome-wide compensation of X-linked genes, while in many ZW systems, compensation is restricted to a minority of dosage-sensitive genes. Why such differences arose is still unclear. Here, we combine comparative genomics, transcriptomics and proteomics to obtain a complete overview of the evolution of gene dosage on the Z-chromosome of <i>Schistosoma</i> parasites. We compare the Z-chromosome gene content of African (<i>Schistosoma mansoni</i> and <i>S. haematobium</i ...[more]