Cognitive Burden of Common Non-antiretroviral Medications in HIV-Infected Women.

ABSTRACT:

Objective

The aging HIV population has increased comorbidity burden and consequently non-antiretroviral medication utilization. Many non-antiretroviral medications have known neurocognitive-adverse effects ("NC-AE medications"). We assessed the cognitive effects of NC-AE medications in HIV+ and HIV- women.

Methods

One thousand five hundred fifty-eight participants (1037 HIV+; mean age 46) from the Women's Interagency HIV Study completed a neuropsychological test battery between 2009 and 2011. The total number of NC-AE medications and subgroups (eg, anticholinergics) were calculated based on self-report. Generalized linear models for non-normal data were used to examine the cognitive burden of medications and factors that exacerbate these effects.

Results

HIV+ women re

SUBMITTER: Rubin LH 

PROVIDER: S-EPMC6092212 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature