Ontology highlight
ABSTRACT:
SUBMITTER: Badr P
PROVIDER: S-EPMC6092444 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Leukemia research reports 20180721
We have investigated the frequency and the effect of <i>KIT</i> mutations on the outcome of patients with CBF-AML. 69 patients (34 pediatrics and 35 adults) with CBF-AML were enrolled in the study. The frequency of <i>KIT</i> mutations was higher in adults compared to pediatrics (22.9% and 14.7%, <i>p</i> = 0.38) respectively. Leukocytosis ≥ 20 × 10<sup>9</sup> /L was significantly associated with pediatrics compared to adults. t(8;21)(q22;22) was significantly associated with thrombocytopenia i ...[more]