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Anxiety is common and independently associated with clinical features of epilepsy.


ABSTRACT: OBJECTIVE:The objective of this study was to assess for independent association of anxiety symptoms with epilepsy localization and other epilepsy-related and demographic factors in a large tertiary care adult epilepsy population. METHODS:Among 540 adults, anxiety was measured by the Symptom Checklist 90-R (SCL-90R) anxiety subscale, and detailed demographics, epilepsy localization, and depression scores (SCL-90R) were collected. High anxiety was defined by SCL-90R anxiety T-score???60. Stepwise multiple logistic regression was carried out to assess for independent association of high anxiety scores with demographic and clinical factors. RESULTS:High anxiety symptoms were present in 46.1% of participants (N?=?250). Focal or unknown epilepsy type and depression scores were independently associated with high anxiety (adjusted odds ratios (OR): 2.89 (95% confidence interval [CI]?=?1.33-6.29, p?=?0.007) and 2.12 (95% CI?=?1.83-2.45, p?

SUBMITTER: Munger Clary HM 

PROVIDER: S-EPMC6093217 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature

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Anxiety is common and independently associated with clinical features of epilepsy.

Munger Clary Heidi M HM   Snively Beverly M BM   Hamberger Marla J MJ  

Epilepsy & behavior : E&B 20180613


<h4>Objective</h4>The objective of this study was to assess for independent association of anxiety symptoms with epilepsy localization and other epilepsy-related and demographic factors in a large tertiary care adult epilepsy population.<h4>Methods</h4>Among 540 adults, anxiety was measured by the Symptom Checklist 90-R (SCL-90R) anxiety subscale, and detailed demographics, epilepsy localization, and depression scores (SCL-90R) were collected. High anxiety was defined by SCL-90R anxiety T-score   ...[more]

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