Serial representation of items during working memory maintenance at letter-selective cortical sites.

ABSTRACT: A key component of working memory is the ability to remember multiple items simultaneously. To understand how the human brain maintains multiple items in memory, we examined direct brain recordings of neural oscillations from neurosurgical patients as they performed a working memory task. We analyzed the data to identify the neural representations of individual memory items by identifying recording sites with broadband gamma activity that varied according to the identity of the letter a subject viewed. Next, we tested a previously proposed model of working memory, which had hypothesized that the neural representations of individual memory items sequentially occurred at different phases of the theta/alpha cycle. Consistent with this model, the phase of the theta/alpha oscillation when stimu

SUBMITTER: Bahramisharif A 

PROVIDER: S-EPMC6093599 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature