Enhanced neural activation with blueberry supplementation in mild cognitive impairment.

ABSTRACT:

Objectives

Preclinical studies have shown that blueberry supplementation can improve cognitive performance and neural function in aged animals and have identified associations between anthocyanins and such benefits. Preliminary human trials also suggest cognitive improvement in older adults, although direct evidence of enhancement of brain function has not been demonstrated. In this study, we investigated the effect of blueberry supplementation on regional brain activation in older adults at risk for dementia.

Methods

In a randomized, double-blind, placebo-controlled trial we performed pre- and post-intervention functional magnetic resonance imaging during a working memory (WM) task to assess the effect of blueberry supplementation on blood oxygen level-dependent (BOLD) sign

SUBMITTER: Boespflug EL 

PROVIDER: S-EPMC6093614 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature