Ontology highlight
ABSTRACT:
SUBMITTER: van Kempen LC
PROVIDER: S-EPMC6094595 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
van Kempen Léon C LC Redpath Margaret M Robert Caroline C Spatz Alan A
Melanoma management 20141101 2
Cutaneous melanoma is associated with strong prognostic phenotypic features, such as gender, Breslow's thickness and ulceration, although the biological significance of these variables is largely unknown. It is likely that these features are surrogates of important biological events rather than directly promoting cutaneous melanoma progression. In this article, we address the molecular mechanisms that drive these phenotypic changes. Furthermore, we present a comprehensive overview of recurrent g ...[more]