Ontology highlight
ABSTRACT:
SUBMITTER: Ferreira LR
PROVIDER: S-EPMC6095079 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Ferreira Ludmila Rodrigues Pinto LR Ferreira Frederico Moraes FM Nakaya Helder Imoto HI Deng Xutao X Cândido Darlan da Silva DD de Oliveira Lea Campos LC Billaud Jean-Noel JN Lanteri Marion C MC Rigaud Vagner Oliveira-Carvalho VO Seielstad Mark M Kalil Jorge J Fernandes Fabio F Ribeiro Antonio Luiz P AL Sabino Ester Cerdeira EC Cunha-Neto Edecio E
The Journal of infectious diseases 20170201 3
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, affects 7 million people in Latin American areas of endemicity. About 30% of infected patients will develop chronic Chagas cardiomyopathy (CCC), an inflammatory cardiomyopathy characterized by hypertrophy, fibrosis, and myocarditis. Further studies are necessary to understand the molecular mechanisms of disease progression. Transcriptome analysis has been increasingly used to identify molecular changes associated with disease ou ...[more]