Ontology highlight
ABSTRACT:
SUBMITTER: Nakamura R
PROVIDER: S-EPMC6095959 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Nakamura Ryuki R Obata Tomohiro T Nojima Ryota R Hashimoto Yohey Y Noguchi Keiichi K Ogawa Takahiro T Yohda Masafumi M
Frontiers in microbiology 20180810
Reductive dehalogenase (RDase) consists of two parts, RdhA and RdhB. RdhA is the catalytic subunit, harboring a cobalamin cofactor and two Fe-S clusters. RdhA is anchored to the cytoplasmic membrane via the membrane anchoring subunit, RdhB. There are many genes encoding RDases in the genome of organohalide-respiring bacteria, including <i>Dehalococcoides</i> spp. However, most genes have not been functionally characterized. Biochemical studies on RDases have been hampered by difficulties encount ...[more]