Browse
Submit Data
Databases
API
Help

Dataset Information

26 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Stretchable Multiresponsive Hydrogel with Actuatable, Shape Memory, and Self-Healing Properties.

ABSTRACT: Smart hydrogels with responsive behaviors have attracted tremendous attention. However, it is still a challenge to synthesize stretchable hydrogels capable of changing their original properties in response to multiple external stimuli. Here, integration of actuation function, shape memory, and self-healing capability in a highly stretchable hydrogel under triple external triggers is achieved by rationally engineering multiple functional moieties. The hydrogel exhibits high stretchability (average relative strain (mm/mm) is >15) and excellent fatigue resistance during 100 loading cycles of 100% strain. Incorporating a moisture-insensitive polymer film with the hydrogel, hydroactuated functionality is demonstrated. Moreover, shape memory and self-healing abilities of the hydrogel are realized by the formation of ionic crosslinking or dynamic borate ester in conditions of multivalent cations and pH, respectively. Deformable plastic flowers are displayed in this work as a proof-of-concept, and it is believed that this smart hydrogel could be used in plenty of frontier fields, such as designing electronic devices, soft robotics, and actuators.

SUBMITTER: Zhang F

PROVIDER: S-EPMC6096994 | biostudies-literature |

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Similar Datasets

An UV-photo and ionic dual responsive interpenetrating network hydrogel with shape memory and self-healing properties.

Project description:Shape memory hydrogels have attracted extensive attention in fields such as artificial tissues, biomimetic devices and diagnostics, and intelligent biosensors. However, the practical applications were hindered by the absence of self-healing capability and multi-stimuli-responsiveness. To address these issues, we developed a shape memory hydrogel with self-healing and dual stimuli-response performance. The hydrogel system was constructed via an interpenetrating network consisting of in situ radical polymerization and host-guest interaction. The hydrogel exhibited rapid self-healing property, which can be stretched after self-healing for 1 min at 25 °C. Besides, the hydrogel displayed varied swelling performance in different light or solvent conditions. Moreover, the hydrogel showed a dual stimuli-responsive shape memory effect to ultraviolet (UV) light and ionic strength in 1 min. Such a shape memory hydrogel with self-healing ability and multi-stimuli-responsive properties will offer an option toward intelligent soft materials for biomedical and bionic research.

| S-EPMC9116958 | biostudies-literature

A Highly Stretchable, Tough, Fast Self-Healing Hydrogel Based on Peptide?Metal Ion Coordination.

Project description:Metal coordination bonds are widely used as the dynamic cross-linkers to construct self-healing hydrogels. However, it remains challenging to independently improve the toughness of metal coordinated hydrogels without affecting the stretchability and self-healing properties, as all these features are directly correlated with the dynamic properties of the same metal coordination bonds. In this work, using histidine-Zn2+ binding as an example, we show that the coordination number (the number of binding sites in each cross-linking ligand) is an important parameter for the mechanical strength of the hydrogels. By increasing the coordination number of the binding site, the mechanical strength of the hydrogels can be greatly improved without sacrificing the stretchability and self-healing properties. By adjusting the peptide and Zn2+ concentrations, the hydrogels can achieve a set of demanding mechanical features, including the Young's modulus of 7-123 kPa, fracture strain of 434-781%, toughness of 630-1350 kJ m-3, and self-healing time of ~1 h. We anticipate the engineered hydrogels can find broad applications in a variety of biomedical fields. Moreover, the concept of improving the mechanical strength of metal coordinated hydrogels by tuning the coordination number may inspire the design of other dynamically cross-linked hydrogels with further improved mechanical performance.

| S-EPMC6632049 | biostudies-literature

Self-Healing and Highly Stretchable Hydrogel for Interfacial Compatible Flexible Paper-Based Micro-Supercapacitor.

Project description:Most reported wearable electronic devices lack self-healing chemistry and flexible function to maintain stable energy output while irreversible damages and complex deformations. In this work, we report a dual-dynamic network electrolyte synthesized by micellar elastomers introduced into strong hydrogel matrix. The gel electrolyte is fabricated by physically cross-linking the borax-polyvinyl alcohol (B-PVA) network as tough matrix and poly (ethylene oxide) (PEO)-poly (propylene oxide) (PPO)-poly (ethylene oxide) (Pluronic) to frame elastic network, followed by immersion in potassium chloride solution. Under the action of dynamic borate ester bond and multi-network hydrogen bond, the as-prepared electrolyte exhibits high stretchability (1535%) and good self-healing efficiency. Based on the electrolyte, we assemble the interfacial compatible micro-supercapacitor (MSC) by multi-walled carbon nanotubes (MWCNT) interdigital electrode printed on cellulosic paper by direct ink writing (DIW) technique. Thanks to the large specific area and compressive deformation resistance of cellulosic paper, the MSC with tightly interfacial contact achieves high volumetric capacitance of 801.9 mF cm-3 at the current density of 20 μA cm-2. In the absence of stimulation of the external environment, the self-healing MSC demonstrates an ideal capacity retention (90.43%) after five physical damaged/healing cycles. Our research provides a clean and effective strategy to construct wearable MSC.

| S-EPMC8070428 | biostudies-literature

Highly Stretchable Shape Memory Self-Soldering Conductive Tape with Reversible Adhesion Switched by Temperature.

Project description:HighlightsShape memory self-soldering tape used as conductive interconnecting material. Perfect shape and conductivity memory performance and anti-fatigue performance. Reversible strong-to-weak adhesion switched by temperature. With practical interest in the future applications of next-generation electronic devices, it is imperative to develop new conductive interconnecting materials appropriate for modern electronic devices to replace traditional rigid solder tin and silver paste of high melting temperature or corrosive solvent requirements. Herein, we design highly stretchable shape memory self-soldering conductive (SMSC) tape with reversible adhesion switched by temperature, which is composed of silver particles encapsulated by shape memory polymer. SMSC tape has perfect shape and conductivity memory property and anti-fatigue ability even under the strain of 90%. It also exhibits an initial conductivity of 2772 S cm-1 and a maximum tensile strain of ~ 100%. The maximum conductivity could be increased to 5446 S cm-1 by decreasing the strain to 17%. Meanwhile, SMSC tape can easily realize a heating induced reversible strong-to-weak adhesion transition for self-soldering circuit. The combination of stable conductivity, excellent shape memory performance, and temperature-switching reversible adhesion enables SMSC tape to serve two functions of electrode and solder simultaneously. This provides a new way for conductive interconnecting materials to meet requirements of modern electronic devices in the future.

| S-EPMC8113436 | biostudies-literature

Bioprinted Injectable Hierarchically Porous Gelatin Methacryloyl Hydrogel Constructs with Shape-Memory Properties.

Project description:Direct injection of cell-laden hydrogels shows high potentials in tissue regeneration for translational therapy. The traditional cell-laden hydrogels are often used as bulk space fillers to tissue defects after injection, likely limiting their structural controllability. On the other hand, patterned cell-laden hydrogel constructs often necessitate invasive surgical procedures. To overcome these problems, herein, we report a unique strategy for encapsulating living human cells in a pore-forming gelatin methacryloyl (GelMA)-based bioink to ultimately produce injectable hierarchically macro-micro-nanoporous cell-laden GelMA hydrogel constructs through three-dimensional (3D) extrusion bioprinting. The hydrogel constructs can be fabricated into various shapes and sizes that are defect-specific. Due to the hierarchically macro-micro-nanoporous structures, the cell-laden hydrogel constructs can readily recover to their original shapes, and sustain high cell viability, proliferation, spreading, and differentiation after compression and injection. Besides, in vivo studies further reveal that the hydrogel constructs can integrate well with the surrounding host tissues. These findings suggest that our unique 3D-bioprinted pore-forming GelMA hydrogel constructs are promising candidates for applications in minimally invasive tissue regeneration and cell therapy.

| S-EPMC7941201 | biostudies-literature

Stretchable supramolecular hydrogels with triple shape memory effect.

Project description:Shape memory polymers based on reversible supramolecular interactions have invoked growing research interest, but still suffer from limitations such as poor mechanical strength and finite shape memory performance. Here, we present a novel mechanical stretchable supramolecular hydrogel with a triple shape memory effect at the macro/micro scale. The introduction of a double network concept into supramolecular shape memory hydrogels endows them with excellent mechanical properties. The design of two non-interfering supramolecular interaction systems of both dynamic phenylboronic (PBA)-diol ester bonds and the chelation of alginate with Ca2+ endues the hydrogel with outstanding triple shape memory functionalities.

| S-EPMC5363791 | biostudies-literature

Chemical and photochemical DNA "gears" reversibly control stiffness, shape-memory, self-healing and controlled release properties of polyacrylamide hydrogels.

Project description:A new class of stimuli-responsive DNA-based polyacrylamide hydrogels is described. They consist of glucosamine-boronate ester-crosslinked polyacrylamide chains being cooperatively bridged by stimuli-responsive nucleic acids. The triggered closure and dissociation of the stimuli-responsive units lead to switchable stiffness properties of the hydrogel. One hydrogel includes glucosamine-boronate esters and K+-ion-stabilized G-quadruplex units as cooperative crosslinkers. The hydrogel bridged by the two motifs reveals high stiffness, whereas the separation of the G-quadruplex bridges by 18-crown-6-ether yields a low stiffness hydrogel. By cyclic treatment of the hydrogel with K+-ions and 18-crown-6-ether, it is reversibly cycled between high and low stiffness states. The second system involves a photo-responsive hydrogel that reveals light-induced switchable stiffness functions. The polyacrylamide chains are cooperatively crosslinked by glucosamine-boronate esters and duplex nucleic acid bridges stabilized by trans-azobenzene intercalator units. The resulting hydrogel reveals high stiffness. Photoisomerization of the trans-azobenzene units to the cis-azobenzene states results in the separation of the duplex nucleic acid bridges and the formation of a low stiffness hydrogel. The control over the stiffness properties of the hydrogel matrices by means of K+-ions/crown ether or photoisomerizable trans-azobenzene/cis-azobenzene units is used to develop shape-memory, self-healing, and controlled drug-release hydrogel materials.

| S-EPMC6346408 | biostudies-literature

Highly Stretchable, Adhesive, Biocompatible, and Antibacterial Hydrogel Dressings for Wound Healing.

Project description:Treatment of wounds in special areas is challenging due to inevitable movements and difficult fixation. Common cotton gauze suffers from incomplete joint surface coverage, confinement of joint movement, lack of antibacterial function, and frequent replacements. Hydrogels have been considered as good candidates for wound dressing because of their good flexibility and biocompatibility. Nevertheless, the adhesive, mechanical, and antibacterial properties of conventional hydrogels are not satisfactory. Herein, cationic polyelectrolyte brushes grafted from bacterial cellulose (BC) nanofibers are introduced into polydopamine/polyacrylamide hydrogels. The 1D polymer brushes have rigid BC backbones to enhance mechanical property of hydrogels, realizing high tensile strength (21-51 kPa), large tensile strain (899-1047%), and ideal compressive property. Positively charged quaternary ammonium groups of tethered polymer brushes provide long-lasting antibacterial property to hydrogels and promote crawling and proliferation of negatively charged epidermis cells. Moreover, the hydrogels are rich in catechol groups and capable of adhering to various surfaces, meeting adhesive demand of large movement for special areas. With the above merits, the hydrogels demonstrate less inflammatory response and faster healing speed for in vivo wound healing on rats. Therefore, the multifunctional hydrogels show stable covering, little displacement, long-lasting antibacteria, and fast wound healing, demonstrating promise in wound dressing.

| S-EPMC8061386 | biostudies-literature

A Self-Healing and Shape Memory Polymer that Functions at Body Temperature.

Project description:Dual-functional polymeric system combining shape memory with self-healing properties has attracted increasingly interests of researchers, as both of these properties are intelligent and promising characteristics. Moreover, shape memory polymer that functions at human body temperature (37 °C) are desirable because of their potential applications in biomedical field. Herein, we designed a polymer network with a permanent covalent crosslinking and abundant weak hydrogen bonds. The former introduces elasticity responsible and maintain the permanent shape, and the latter contributes to the temporary shape via network rearrangement. The obtained PDMS-COO-E polymer films exhibit excellent mechanical properties and the capability to efficiently self-heal for 6 h at room temperature. Furthermore, the samples turn from a viscous state into an elastic state at 37 °C. Therefore, this polymer has shape memory effects triggered by body temperature. This unique material will have a wide range of applications in many fields, containing wearable electronics, biomedical devices, and 4D printing.

| S-EPMC6767172 | biostudies-literature

The Effect of 4-Octyldecyloxybenzoic Acid on Liquid-Crystalline Polyurethane Composites with Triple-Shape Memory and Self-Healing Properties.

Project description:To better understand shape memory materials and self-healing materials, a new series of liquid-crystalline shape memory polyurethane (LC-SMPU) composites, named SMPU-OOBAm, were successfully prepared by incorporating 4-octyldecyloxybenzoic acid (OOBA) into the PEG-based SMPU. The effect of OOBA on the structure, morphology, and properties of the material has been carefully investigated. The results demonstrate that SMPU-OOBAm has liquid crystalline properties, triple-shape memory properties, and self-healing properties. The incorporated OOBA promotes the crystallizability of both soft and hard segments of SMPU, and the crystallization rate of the hard segment of SMPU decreases when the OOBA-content increases. Additionally, the SMPU-OOBAm forms a two-phase separated structure (SMPU phase and OOBA phase), and it shows two-step modulus changes upon heating. Therefore, the SMPU-OOBAm exhibits triple-shape memory behavior, and the shape recovery ratio decreases with an increase in the OOBA content. Finally, SMPU-OOBAm exhibits self-healing properties. The new mechanism can be ascribed to the heating-induced "bleeding" of OOBA in the liquid crystalline state and the subsequent re-crystallization upon cooling. This successful combination of liquid crystalline properties, triple-shape memory properties, and self-healing properties make the SMPU-OOBAm composites ideal for many promising applications in smart optical devices, smart electronic devices, and smart sensors.

| S-EPMC5457044 | biostudies-other

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data