Ontology highlight
ABSTRACT:
SUBMITTER: Acuna A
PROVIDER: S-EPMC6097807 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Acuna Andrea A Drakopoulos Michael A MA Leng Yue Y Goergen Craig J CJ Calve Sarah S
Developmental biology 20180117 2
The extracellular matrix (ECM) plays a crucial role in embryogenesis, serving both as a substrate to which cells attach and as an active regulator of cell behavior. However, little is known about the spatiotemporal expression patterns and 3D structure of ECM proteins during embryonic development. The lack of suitable methods to visualize the embryonic ECM is largely responsible for this gap, posing a major technical challenge for biologists and tissue engineers. Here, we describe a method of vie ...[more]