Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports.
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ABSTRACT:
SUBMITTER: Adams JW
PROVIDER: S-EPMC6097837 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
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Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports.
Adams Jason W JW Alvarez Victor E VE Mez Jesse J Huber Bertrand R BR Tripodis Yorghos Y Xia Weiming W Meng Gaoyuan G Kubilus Caroline A CA Cormier Kerry K Kiernan Patrick T PT Daneshvar Daniel H DH Chua Alicia S AS Svirsky Sarah S Nicks Raymond R Abdolmohammadi Bobak B Evers Laney L Solomon Todd M TM Cherry Jonathan D JD Aytan Nurgul N Mahar Ian I Devine Sherral S Auerbach Sanford S Alosco Michael L ML Nowinski Christopher J CJ Kowall Neil W NW Goldstein Lee E LE Dwyer Brigid B Katz Douglas I DI Cantu Robert C RC Stern Robert A RA Au Rhoda R McKee Ann C AC Stein Thor D TD
Journal of neuropathology and experimental neurology 20180901 9
Traumatic brain injury has been associated with increased risk of Parkinson disease and parkinsonism, and parkinsonism and Lewy body disease (LBD) can occur with chronic traumatic encephalopathy (CTE). To test whether contact sports and CTE are associated with LBD, we compared deceased contact sports athletes (n = 269) to cohorts from the community (n = 164) and the Boston University Alzheimer disease (AD) Center (n = 261). Participants with CTE and LBD were more likely to have β-amyloid deposit ...[more]
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