Genetic thrombophilia variants and risk for preeclampsia among American Indians.
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ABSTRACT:
SUBMITTER: Best LG
PROVIDER: S-EPMC6097878 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Publications
Genetic thrombophilia variants and risk for preeclampsia among American Indians.
Best Lyle G LG Dorsam Sheri T ST Nadeau Melanie M Burd Larry L Anderson Cindy M CM
Hypertension in pregnancy 20090201 1
<h4>Objective</h4>To determine the prevalence of thrombophilic genetic variants in an American Indian population and determine if they are associated with preeclampsia.<h4>Methods</h4>A total of 87 cases, 165 controls and an additional 75 population-based controls were genotyped for two thrombophilic polymorphisms.<h4>Results</h4>The allelic prevalence of the factor V Leiden and 20210 G/A prothrombin variants in this population was 2.1% and 0.5% respectively. No statistically significant associa ...[more]
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