Ontology highlight
ABSTRACT:
SUBMITTER: Kidd BE
PROVIDER: S-EPMC6097920 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Kidd Bryce E BE Mashni Jamil A JA Limbach Miranda N MN Shi Fan F Chekmenev Eduard Y EY Hou Yuqing Y Goodson Boyd M BM
Chemistry (Weinheim an der Bergstrasse, Germany) 20180629 42
We show the simultaneous generation of hyperpolarized <sup>13</sup> C-labeled acetate and <sup>15</sup> N-labeled imidazole following spin-relay of hyperpolarization and hydrolysis of the acetyl moiety on 1-<sup>13</sup> C-<sup>15</sup> N<sub>2</sub> -acetylimidazole. Using SABRE-SHEATH (Signal Amplification by Reversible Exchange in SHield Enables Alignment Transfer to Heteronuclei), transfer of spin order occurs from parahydrogen to acetylimidazole <sup>15</sup> N atoms and the acetyl <sup>13< ...[more]