Ontology highlight
ABSTRACT:
SUBMITTER: Kim JE
PROVIDER: S-EPMC6098055 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Kim Jeong Eun JE Hong Ji Won JW Lee Hannah S HS Kim Wankyu W Lim Jisun J Cho Yoon Shin YS Kwon Ho Jeong HJ
Scientific reports 20180817 1
Ubiquinol cytochrome c reductase binding protein (UQCRB) is known to play crucial roles in the development of various types of diseases. However, the link between UQCRB and microRNAs remains unknown. In the present study, we performed microRNA sequencing of mutant UQCRB-expressing stable cell lines that exhibited pro-oncogenic activities caused by expression of the mutant UQCRB gene. Results showed that hsa-miR-10a-5p was significantly downregulated in the mutant UQCRB-expressing cell lines. Fur ...[more]