High expression of EZH2 as a marker for the differential diagnosis of malignant and benign myogenic tumors.
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ABSTRACT:
SUBMITTER: Zhang N
PROVIDER: S-EPMC6098067 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
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High expression of EZH2 as a marker for the differential diagnosis of malignant and benign myogenic tumors.
Zhang Ning N Zeng Zhi Z Li Shaobo S Wang Fei F Huang Peng P
Scientific reports 20180817 1
Overlap in morphologic features between malignant and benign myogenic tumors, such as leiomyosarcoma (LMS) vs. leiomyoma as well as rhabdomyosarcoma (RMS) vs. rhabdomyoma, often makes differential diagnosis difficult and challenging. Here the expressions of Enhancer of Zeste Homolog 2 (EZH2), Suppressor of Zeste 12 (SUZ12), retinoblastoma protein associated protein 46 (RbAp46), Embryonic Ectoderm Development (EED) and ki-67 protein were detected by immunohistochemistry to evaluate their values i ...[more]
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