Ontology highlight
ABSTRACT:
SUBMITTER: Xu H
PROVIDER: S-EPMC6099640 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Xu Huiyou H Chen Ting T Huang Luanbin L Shen Qiuju Q Lian Zengwei Z Shi Yan Y Ouyang Ming-An MA Song Liyan L
Molecules (Basel, Switzerland) 20180621 7
A efficient 2-step protocol has been applied for the synthesis of Lansiumamide B (<i>N</i>-methyl-<i>N</i>-<i>cis</i>-styryl-cinnamamide, <b>2</b>) derivatives by various substitution on the amide nitrogen with alkyl, allyl, propargyl, benzyl or ester groups. The structures of nine new compounds were characterized by HRMS, ¹H NMR, and <sup>13</sup>C NMR spectra. These compounds were tested in vitro against 10 strains of phytopathogenic fungi and showed a wide antifungal spectrum. The relationshi ...[more]