Ontology highlight
ABSTRACT:
SUBMITTER: Reddy MC
PROVIDER: S-EPMC6100235 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Reddy Mallu Chenna MC Jeganmohan Masilamani M
Chemical science 20170323 5
A concise total synthesis of aristolactam alkaloids by a synergistic combination of C-H bond activation and dehydro-Diels-Alder reactions is described. To achieve the synthesis two new synthetic methodologies, namely the oxidative cyclization of benzamides with vinyl sulfone leading to 3-methyleneisoindolin-1-ones <i>via</i> a ruthenium-catalyzed C-H bond activation, and a dehydro-Diels-Alder reaction followed by the fluoride ion mediated desulfonylation of 3-methyleneisoindolin-1-ones with benz ...[more]