Ketamine-Associated Brain Changes: A Review of the Neuroimaging Literature.
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ABSTRACT:
SUBMITTER: Ionescu DF
PROVIDER: S-EPMC6102096 | biostudies-literature | 2018 Nov/Dec
REPOSITORIES: biostudies-literature
Publications
Ketamine-Associated Brain Changes: A Review of the Neuroimaging Literature.
Ionescu Dawn F DF Felicione Julia M JM Gosai Aishwarya A Cusin Cristina C Shin Philip P Shapero Benjamin G BG Deckersbach Thilo T
Harvard review of psychiatry 20181101 6
Major depressive disorder (MDD) is one of the most prevalent conditions in psychiatry. Patients who do not respond to traditional monoaminergic antidepressant treatments have an especially difficult-to-treat type of MDD termed treatment-resistant depression. Subanesthetic doses of ketamine-a glutamatergic modulator-have shown great promise for rapidly treating patients with the most severe forms of depression. As such, ketamine represents a promising probe for understanding the pathophysiology o ...[more]
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