Ontology highlight
ABSTRACT:
SUBMITTER: Chevalier M
PROVIDER: S-EPMC6103258 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Chevalier Morgan M Vermij Sarah H SH Wyler Kurt K Gillet Ludovic L Keller Irene I Abriel Hugues H
Scientific data 20180821
Mice are used universally as model organisms for studying heart physiology, and a plethora of genetically modified mouse models exist to study cardiac disease. Transcriptomic data for whole-heart tissue are available, but not yet for isolated ventricular cardiomyocytes. Our lab therefore collected comprehensive RNA-seq data from wildtype murine ventricular cardiomyocytes as well as from knockout models of the ion channel regulators CASK, dystrophin, and SAP97. We also elucidate ion channel expre ...[more]