Ontology highlight
ABSTRACT:
SUBMITTER: Scott CL
PROVIDER: S-EPMC6104815 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Immunity 20180731 2
Heterogeneity between different macrophage populations has become a defining feature of this lineage. However, the conserved factors defining macrophages remain largely unknown. The transcription factor ZEB2 is best described for its role in epithelial to mesenchymal transition; however, its role within the immune system is only now being elucidated. We show here that Zeb2 expression is a conserved feature of macrophages. Using Clec4f-cre, Itgax-cre, and Fcgr1-cre mice to target five different m ...[more]