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Live-stream characterization of cadmium-induced cell death using visible CdTe-QDs.

ABSTRACT: Characterization of cell death currently requires the use of indirect markers, which has largely limited the ability to monitor cell death processes inside the cell. Here, we introduce a new method for the characterization of cell death mechanisms using cadmium telluride quantum dots (CdTe-QDs). Using visible CdTe-QDs with mesenchymal cells (e.g. synoviocytes), live-stream imaging allowed for visualization of cadmium-induced cell death, combining characteristics of apoptosis and autophagy. Initially, similar anti-proliferative effect was observed between 10?µg/ml Cd2+ and CdTe-QDs at 24?h (cell index/cell density ratio decreased from 0.6 to -16.6, p?

SUBMITTER: Filali S

PROVIDER: S-EPMC6105671 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature

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Live-stream characterization of cadmium-induced cell death using visible CdTe-QDs.

Filali Samira S Geloën Alain A Lysenko Vladimir V Pirot Fabrice F Miossec Pierre P

Scientific reports 20180822 1

Characterization of cell death currently requires the use of indirect markers, which has largely limited the ability to monitor cell death processes inside the cell. Here, we introduce a new method for the characterization of cell death mechanisms using cadmium telluride quantum dots (CdTe-QDs). Using visible CdTe-QDs with mesenchymal cells (e.g. synoviocytes), live-stream imaging allowed for visualization of cadmium-induced cell death, combining characteristics of apoptosis and autophagy. Initi ...[more]

PMID: 30135565

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