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Strategies for reducing speckle noise in digital holography.

ABSTRACT: Digital holography (DH) has emerged as one of the most effective coherent imaging technologies. The technological developments of digital sensors and optical elements have made DH the primary approach in several research fields, from quantitative phase imaging to optical metrology and 3D display technologies, to name a few. Like many other digital imaging techniques, DH must cope with the issue of speckle artifacts, due to the coherent nature of the required light sources. Despite the complexity of the recently proposed de-speckling methods, many have not yet attained the required level of effectiveness. That is, a universal denoising strategy for completely suppressing holographic noise has not yet been established. Thus the removal of speckle noise from holographic images represents a bottleneck for the entire optics and photonics scientific community. This review article provides a broad discussion about the noise issue in DH, with the aim of covering the best-performing noise reduction approaches that have been proposed so far. Quantitative comparisons among these approaches will be presented.

SUBMITTER: Bianco V

PROVIDER: S-EPMC6106996 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Strategies for reducing speckle noise in digital holography.

Bianco Vittorio V Memmolo Pasquale P Leo Marco M Montresor Silvio S Distante Cosimo C Paturzo Melania M Picart Pascal P Javidi Bahram B Ferraro Pietro P

Light, science & applications 20180801

Digital holography (DH) has emerged as one of the most effective coherent imaging technologies. The technological developments of digital sensors and optical elements have made DH the primary approach in several research fields, from quantitative phase imaging to optical metrology and 3D display technologies, to name a few. Like many other digital imaging techniques, DH must cope with the issue of speckle artifacts, due to the coherent nature of the required light sources. Despite the complexity ...[more]

PMID: 30839600

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Project description:Quantitative stiffness information can be a powerful aid for tumor or fibrosis diagnosis. Currently, very promising elastography approaches developed for non-contact biomedical imaging are based on transient shear-waves imaging. Transient elastography offers quantitative stiffness information by tracking the propagation of a wave front. The most common method used to compute stiffness from the acquired propagation movie is based on shear-wave time-of-flight calculations. We introduce an approach to transient shear-wave elastography with spatially coherent sources, able to yield full-field quantitative stiffness maps with reduced artifacts compared to typical artifacts observed in time-of-flight. A noise-correlation algorithm developed for passive elastography is adapted to spatially coherent narrow or any band sources. This noise-correlation-inspired (NCi) method is employed in parallel with a classic time-of-flight approach. Testing is done on simulation images, experimental validation is conducted with a digital holography setup on controlled homogeneous samples, and full-field quantitative stiffness maps are presented for heterogeneous samples and ex-vivo biological tissues. The NCi approach is first validated on simulations images. Stiffness images processed by the NCi approach on simulated inclusions display significantly less artifacts than with a time-of-flight reconstruction. The adaptability of the NCi algorithm to narrow or any band shear-wave sources was tested successfully. Experimental testing on homogeneous samples demonstrates similar values for both the time-of-flight and the NCi approach. Soft inclusions in agarose sample could be resolved using the NCi method and feasibility on ex-vivo biological tissues is presented. The presented NCi approach was successful in computing quantitative full-field stiffness maps with narrow and broadband source signals on simulation and experimental images from a digital holography setup. Results in heterogeneous media show that the NCi approach could provide stiffness maps with less artifacts than with time-of-flight, demonstrating that a NCi algorithm is a promising approach for shear-wave transient elastography with spatially coherent sources.

Dataset Information

Strategies for reducing speckle noise in digital holography.

Publications

Strategies for reducing speckle noise in digital holography.

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