Ontology highlight
ABSTRACT:
SUBMITTER: Wienecke CFR
PROVIDER: S-EPMC6107374 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Wienecke Carl F R CFR Leong Jonathan C S JCS Clandinin Thomas R TR
Neuron 20180726 4
While linear mechanisms lay the foundations of feature selectivity in many brain areas, direction selectivity in the elementary motion detector (EMD) of the fly has become a paradigm of nonlinear neuronal computation. We have bridged this divide by demonstrating that linear spatial summation can generate direction selectivity in the fruit fly Drosophila. Using linear systems analysis and two-photon imaging of a genetically encoded voltage indicator, we measure the emergence of direction-selectiv ...[more]