Dataset Information

Computing Multivariate Effect Sizes and Their Sampling Covariance Matrices With Structural Equation Modeling: Theory, Examples, and Computer Simulations.

ABSTRACT: In the social and behavioral sciences, it is recommended that effect sizes and their sampling variances be reported. Formulas for common effect sizes such as standardized and raw mean differences, correlation coefficients, and odds ratios are well known and have been well studied. However, the statistical properties of multivariate effect sizes have received less attention in the literature. This study shows how structural equation modeling (SEM) can be used to compute multivariate effect sizes and their sampling covariance matrices. We focus on the standardized mean difference (multiple-treatment and multiple-endpoint studies) with or without the assumption of the homogeneity of variances (or covariance matrices) in this study. Empirical examples were used to illustrate the procedures in R. Two computer simulation studies were used to evaluate the empirical performance of the SEM approach. The findings suggest that in multiple-treatment and multiple-endpoint studies, when the assumption of the homogeneity of variances (or covariance matrices) is questionable, it is preferable not to impose this assumption when estimating the effect sizes. Implications and further directions are discussed.

SUBMITTER: Cheung MW

PROVIDER: S-EPMC6107852 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Publications

Computing Multivariate Effect Sizes and Their Sampling Covariance Matrices With Structural Equation Modeling: Theory, Examples, and Computer Simulations.

Cheung Mike W-L MW

Frontiers in psychology 20180817

In the social and behavioral sciences, it is recommended that effect sizes and their sampling variances be reported. Formulas for common effect sizes such as standardized and raw mean differences, correlation coefficients, and odds ratios are well known and have been well studied. However, the statistical properties of multivariate effect sizes have received less attention in the literature. This study shows how structural equation modeling (SEM) can be used to compute multivariate effect sizes ...[more]

PMID: 30174628

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Project description:This article investigates a form of rank deficiency in phenotypic covariance matrices derived from geometric morphometric data, and its impact on measures of phenotypic integration. We first define a type of rank deficiency based on information theory then demonstrate that this deficiency impairs the performance of phenotypic integration metrics in a model system. Lastly, we propose methods to treat for this information rank deficiency. Our first goal is to establish how the rank of a typical geometric morphometric covariance matrix relates to the information entropy of its eigenvalue spectrum. This requires clear definitions of matrix rank, of which we define three: the full matrix rank (equal to the number of input variables), the mathematical rank (the number of nonzero eigenvalues), and the information rank or "effective rank" (equal to the number of nonredundant eigenvalues). We demonstrate that effective rank deficiency arises from a combination of methodological factors-Generalized Procrustes analysis, use of the correlation matrix, and insufficient sample size-as well as phenotypic covariance. Secondly, we use dire wolf jaws to document how differences in effective rank deficiency bias two metrics used to measure phenotypic integration. The eigenvalue variance characterizes the integration change incorrectly, and the standardized generalized variance lacks the sensitivity needed to detect subtle changes in integration. Both metrics are impacted by the inclusion of many small, but nonzero, eigenvalues arising from a lack of information in the covariance matrix, a problem that usually becomes more pronounced as the number of landmarks increases. We propose a new metric for phenotypic integration that combines the standardized generalized variance with information entropy. This metric is equivalent to the standardized generalized variance but calculated only from those eigenvalues that carry nonredundant information. It is the standardized generalized variance scaled to the effective rank of the eigenvalue spectrum. We demonstrate that this metric successfully detects the shift of integration in our dire wolf sample. Our third goal is to generalize the new metric to compare data sets with different sample sizes and numbers of variables. We develop a standardization for matrix information based on data permutation then demonstrate that Smilodon jaws are more integrated than dire wolf jaws. Finally, we describe how our information entropy-based measure allows phenotypic integration to be compared in dense semilandmark data sets without bias, allowing characterization of the information content of any given shape, a quantity we term "latent dispersion". [Canis dirus; Dire wolf; effective dispersion; effective rank; geometric morphometrics; information entropy; latent dispersion; modularity and integration; phenotypic integration; relative dispersion.].

Dataset Information

Computing Multivariate Effect Sizes and Their Sampling Covariance Matrices With Structural Equation Modeling: Theory, Examples, and Computer Simulations.

Publications

Computing Multivariate Effect Sizes and Their Sampling Covariance Matrices With Structural Equation Modeling: Theory, Examples, and Computer Simulations.

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