Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez-Duarte J
PROVIDER: S-EPMC6109136 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Rodriguez-Duarte Jorge J Dapueto Rosina R Galliussi Germán G Turell Lucía L Kamaid Andrés A Khoo Nicholas K H NKH Schopfer Francisco J FJ Freeman Bruce A BA Escande Carlos C Batthyány Carlos C Ferrer-Sueta Gerardo G López Gloria V GV
Scientific reports 20180824 1
Inflammation plays a major role in the onset and development of chronic non-communicable diseases like obesity, cardiovascular diseases and cancer. Combined, these diseases represent the most common causes of death worldwide, thus development of novel pharmacological approaches is crucial. Electrophilic nitroalkenes derived from fatty acids are formed endogenously and exert anti-inflammatory actions by the modification of proteins involved in inflammation signaling cascades. We have developed no ...[more]