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Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus.

ABSTRACT: Three new heptelidic acid derivatives (1-3) including two new dimeric esters and two known heptelidic acid analogues (4 and 5) were isolated from the solid culture of mushroom Lentinellus ursinus. The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopic data. The biosynthetic origin of compounds 1-5 was postulated. Compounds 1-5 exhibited no antibacterial activity against Staphylococcus aureus and Escherichia coli at the dose of 100 ?M.

SUBMITTER: Liu L

PROVIDER: S-EPMC6109445 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus.

Liu Li L Han Jun-Jie JJ Xu Tian-Shun TS Liu Rui-Xing RX Bao Li L Liu Hong-Wei HW

Natural products and bioprospecting 20180522 5

Three new heptelidic acid derivatives (1-3) including two new dimeric esters and two known heptelidic acid analogues (4 and 5) were isolated from the solid culture of mushroom Lentinellus ursinus. The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopic data. The biosynthetic origin of compounds 1-5 was postulated. Compounds 1-5 exhibited no antibacterial activity against Staphylococcus aureus and Escherichia coli at the dose of 100 μM. ...[more]

PMID: 29790088

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