Ontology highlight
ABSTRACT:
SUBMITTER: Rossi E
PROVIDER: S-EPMC6110831 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Rossi Elio E Falcone Marilena M Molin Søren S Johansen Helle Krogh HK
Nature communications 20180827 1
Life-long bacterial infections in cystic fibrosis (CF) airways constitute an excellent model both for persistent infections and for microbial adaptive evolution in complex dynamic environments. Using high-resolution transcriptomics applied on CF sputum, we profile transcriptional phenotypes of Pseudomonas aeruginosa populations in patho-physiological conditions. Here we show that the soft-core genome of genetically distinct populations, while maintaining transcriptional flexibility, shares a com ...[more]