Dataset Information

Association of airborne particles, protein, and endotoxin with emergency department visits for asthma in Kyoto, Japan.

ABSTRACT:

Background

The health effects of biological aerosols on the respiratory system are unclear. The purpose of this study was to clarify the association of airborne particle, protein, and endotoxin with emergency department visits for asthma in Kyoto City, Japan.

Methods

We collected data on emergency department visits at a hospital in Kyoto from September 2014 to May 2016. Fine (aerodynamic diameter ≤ 2.5 μm) and coarse (≥ 2.5 μm) particles were collected in Kyoto, and protein and endotoxin levels were analyzed. The association of the levels of particles, protein, endotoxin, and meteorological factors (temperature, relative humidity, wind speed, and air pressure) with emergency department visits for asthma was estimated.

Results

There were 1 to 15 emergency department visits for asthma per week, and the numbers of visits increased in the autumn and spring, namely many weeks in September, October, and April. Weekly concentration of protein in fine particles was markedly higher than that in coarse particles, and protein concentration in fine particles was high in spring months. Weekly endotoxin concentrations in fine and coarse particles were high in autumn months, including September 2014 and 2015. Even after adjusting for meteorological factors, the concentrations of coarse particles and endotoxin in both particles were significant factors on emergency department visits for asthma.

Conclusions

Our results suggest that atmospheric coarse particles and endotoxin are significantly associated with an increased risk of asthma exacerbation.

SUBMITTER: Khan MS

PROVIDER: S-EPMC6114267 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature

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Publications

Association of airborne particles, protein, and endotoxin with emergency department visits for asthma in Kyoto, Japan.

Khan Mohammad Shahriar MS Coulibaly Souleymane S Matsumoto Takahiro T Yano Yoshitaka Y Miura Makoto M Nagasaka Yukio Y Shima Masayuki M Yamagishi Nobuyuki N Wakabayashi Keiji K Watanabe Tetsushi T

Environmental health and preventive medicine 20180828 1

<h4>Background</h4>The health effects of biological aerosols on the respiratory system are unclear. The purpose of this study was to clarify the association of airborne particle, protein, and endotoxin with emergency department visits for asthma in Kyoto City, Japan.<h4>Methods</h4>We collected data on emergency department visits at a hospital in Kyoto from September 2014 to May 2016. Fine (aerodynamic diameter ≤ 2.5 μm) and coarse (≥ 2.5 μm) particles were collected in Kyoto, and protein and en ...[more]

PMID: 30153806

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Dataset Information

Association of airborne particles, protein, and endotoxin with emergency department visits for asthma in Kyoto, Japan.

Background

Methods

Results

Conclusions

Publications

Association of airborne particles, protein, and endotoxin with emergency department visits for asthma in Kyoto, Japan.

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