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Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis.


ABSTRACT: Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave infrared fluorescent nanoparticles, which are currently under investigation for peritoneal carcinomatosis fluorescence imaging. We also highlight the main ways to improve the safety of nanoparticles, for fulfilling prerequisites of clinical application.

SUBMITTER: Mangeolle T 

PROVIDER: S-EPMC6116267 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis.

Mangeolle Tristan T   Yakavets Ilya I   Marchal Sophie S   Debayle Manon M   Pons Thomas T   Bezdetnaya Lina L   Marchal Frédéric F  

Nanomaterials (Basel, Switzerland) 20180726 8


Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave infrared fluorescent nanoparticles, which are currently under investigation for peritoneal carcinomatosis fluorescence imaging. We also highlight the main ways to improve the safety of nanoparticles,  ...[more]

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