Ontology highlight
ABSTRACT:
SUBMITTER: Deev R
PROVIDER: S-EPMC6116753 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Therapeutic advances in cardiovascular disease 20180711 9
<h4>Background</h4>The effective treatment of chronic lower limb ischemia is one of the most challenging issues confronting vascular surgeons. Current pharmacological therapies play an auxiliary role and cannot prevent disease progression, and new treatment methods are needed. In 2011, a plasmid VEGF65-gene therapy drug was approved in Russia for the treatment of chronic lower limb ischemia ( ClinicalTrials.gov identifier: NCT03068585). The objective of this follow-up study was to evaluate the l ...[more]