Ontology highlight
ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC6116903 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Li Yuchao Y Lee Minji M Kim Nury N Wu Guoyu G Deng Difan D Kim Jin Man JM Liu Xuedong X Heo Won Do WD Zi Zhike Z
ACS synthetic biology 20180112 2
Cells employ signaling pathways to make decisions in response to changes in their immediate environment. Transforming growth factor beta (TGF-β) is an important growth factor that regulates many cellular functions in development and disease. Although the molecular mechanisms of TGF-β signaling have been well studied, our understanding of this pathway is limited by the lack of tools that allow the control of TGF-β signaling with high spatiotemporal resolution. Here, we developed an optogenetic sy ...[more]