Ontology highlight
ABSTRACT:
SUBMITTER: Tijani M
PROVIDER: S-EPMC6118154 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Tijani Maha M Munis Altar M AM Perry Christopher C Sanber Khaled K Ferraresso Marta M Mukhopadhyay Tarit T Themis Michael M Nisoli Ilaria I Mattiuzzo Giada G Collins Mary K MK Takeuchi Yasuhiro Y
Molecular therapy. Methods & clinical development 20180807
Retroviral and lentiviral vectors often use the envelope G protein from the vesicular stomatitis virus Indiana strain (VSVind.G). However, lentivector producer cell lines that stably express VSVind.G have not been reported, presumably because of its cytotoxicity, preventing simple scale-up of vector production. Interestingly, we showed that VSVind.G and other vesiculovirus G from the VSV New Jersey strain (VSVnj), Cocal virus (COCV), and Piry virus (PIRYV) could be constitutively expressed and s ...[more]