Ontology highlight
ABSTRACT:
SUBMITTER: Serrano Negron YL
PROVIDER: S-EPMC6118319 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Serrano Negron Yazmin L YL Hansen Nancy F NF Harbison Susan T ST
G3 (Bethesda, Md.) 20180830 9
Understanding how genomic variation causes differences in observable phenotypes remains a major challenge in biology. It is difficult to trace the sequence of events originating from genomic variants to changes in transcriptional responses or protein modifications. Ideally, one would conduct experiments with individuals that are at either extreme of the trait of interest, but such resources are often not available. Further, advances in genome editing will enable testing of candidate polymorphism ...[more]