A Connectome-wide Functional Signature of Transdiagnostic Risk for Mental Illness.
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ABSTRACT:
SUBMITTER: Elliott ML
PROVIDER: S-EPMC6119080 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
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A Connectome-wide Functional Signature of Transdiagnostic Risk for Mental Illness.
Elliott Maxwell L ML Romer Adrienne A Knodt Annchen R AR Hariri Ahmad R AR
Biological psychiatry 20180410 6
<h4>Background</h4>High rates of comorbidity, shared risk, and overlapping therapeutic mechanisms have led psychopathology research toward transdiagnostic dimensional investigations of clustered symptoms. One influential framework accounts for these transdiagnostic phenomena through a single general factor, sometimes referred to as the p factor, associated with risk for all common forms of mental illness.<h4>Methods</h4>We build on previous research identifying unique structural neural correlate ...[more]
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