Ontology highlight
ABSTRACT:
SUBMITTER: Kim HH
PROVIDER: S-EPMC6121498 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Kim Hyuk-Hoon HH Choi Sangchun S
International journal of molecular sciences 20180813 8
Carbon monoxide (CO) is being increasingly recognized as a potential therapeutic with important signaling functions in various diseases. Carbon monoxide-releasing molecules (CORMs) show anti-apoptotic, anti-inflammatory, and anti-oxidant effects on the tissues of organisms, thus contributing to tissue homeostasis. An increase in reactive oxygen species production from the mitochondria after exposure to CO is also considered one of the underlying mechanisms of cardioprotection, although mitochond ...[more]