Ontology highlight
ABSTRACT:
SUBMITTER: Martinez-Bueno M
PROVIDER: S-EPMC6121630 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Martínez-Bueno Manuel M Oparina Nina N Dozmorov Mikhail G MG Marion Miranda C MC Comeau Mary E ME Gilkeson Gary G Kamen Diane D Weisman Michael M Salmon Jane J McCune Joseph W JW Harley John B JB Kimberly Robert R James Judith A JA Merrill Joan J Montgomery Courtney C Langefeld Carl D CD Alarcón-Riquelme Marta E ME
International journal of molecular sciences 20180808 8
<i>BANK1</i> is a susceptibility gene for several systemic autoimmune diseases in several populations. Using the genome-wide association study (GWAS) data from Europeans (EUR) and African Americans (AA), we performed an extensive fine mapping of ankyrin repeats 1 (<i>BANK1</i>). To increase the SNP density, we used imputation followed by univariate and conditional analysis, combined with a haplotypic and expression quantitative trait locus (eQTL) analysis. The data from Europeans showed that the ...[more]