Ontology highlight
ABSTRACT:
SUBMITTER: Bahmad HF
PROVIDER: S-EPMC6121836 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Bahmad Hisham F HF Cheaito Katia K Chalhoub Reda M RM Hadadeh Ola O Monzer Alissar A Ballout Farah F El-Hajj Albert A Mukherji Deborah D Liu Yen-Nien YN Daoud Georges G Abou-Kheir Wassim W
Frontiers in oncology 20180828
Cancer Stem Cells (CSCs) are a sub-population of cells, identified in most tumors, responsible for the initiation, recurrence, metastatic potential, and resistance of different malignancies. In prostate cancer (PCa), CSCs were identified and thought to be responsible for the generation of the lethal subtype, commonly known as Castration-Resistant Prostate Cancer (CRPC). <i>In vitro</i> models to investigate the properties of CSCs in PCa are highly required. Sphere-formation assay is an <i>in vit ...[more]