Ontology highlight
ABSTRACT:
SUBMITTER: Nemoto M
PROVIDER: S-EPMC6122309 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Respiratory medicine case reports 20180827
Myeloperoxidase antineutrophil cytoplasmic autoantibody (MPO-ANCA) is well-known as a serological marker for small-vessel vasculitis. However, when a smoker with interstitial lung disease (ILD) exhibits serum ANCA positivity without systemic vasculitis, diagnosis is a matter of debate; the relationship between smoking and ANCA is unknown. We report a case of combined pulmonary fibrosis and emphysema (CPFE) with elevated MPO-ANCA. Surgical lung biopsy showed emphysema and fibrotic interstitial pn ...[more]