FADS1-FADS2 and ELOVL2 gene polymorphisms in susceptibility to autism spectrum disorders in Chinese children.
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ABSTRACT:
SUBMITTER: Sun C
PROVIDER: S-EPMC6122697 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Publications
FADS1-FADS2 and ELOVL2 gene polymorphisms in susceptibility to autism spectrum disorders in Chinese children.
Sun Caihong C Zou Mingyang M Wang Xuelai X Xia Wei W Ma Yongjuan Y Liang Shuang S Hao Yanqiu Y Wu Lijie L Fu Songbin S
BMC psychiatry 20180904 1
<h4>Backgroud</h4>Autism spectrum disorders (ASD) are a complex group of neurodevelopmental disorders with a genetic basis. The role of long-chain polyunsaturated fatty acids (LC-PUFAs) and the occurrence of autism has been the focus of many recent studies. The present study investigates whether genetic variants of the fatty acid desaturase (FADS) 1/2 and elongation of very long-chain fatty acids protein (ELOVL) 2 genes, which are involved in LC-PUFA metabolism, are associated with ASD risk.<h4> ...[more]
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