Hypertension genomics and cardiovascular prevention.
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ABSTRACT:
SUBMITTER: Ng FL
PROVIDER: S-EPMC6123211 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Publications
Hypertension genomics and cardiovascular prevention.
Ng Fu Liang FL Warren Helen R HR Caulfield Mark J MJ
Annals of translational medicine 20180801 15
Hypertension continues to be a major risk factor for global mortality, and recent genome-wide association studies (GWAS) have expanded in size, leading to the identification of further genetic loci influencing blood pressure. In light of the new knowledge from the largest cardiovascular GWAS to date, we review the potential impact of genomics on discovering potential drug targets, risk stratification with genetic risk scores, drug selection with pharmacogenetics, and exploring insights provided ...[more]
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