Ontology highlight
ABSTRACT:
SUBMITTER: Tay TL
PROVIDER: S-EPMC6123921 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Tay Tuan Leng TL Sagar Dautzenberg Jana J Grün Dominic D Prinz Marco M
Acta neuropathologica communications 20180905 1
Microglia are brain immune cells that constantly survey their environment to maintain homeostasis. Enhanced microglial reactivity and proliferation are typical hallmarks of neurodegenerative diseases. Whether specific disease-linked microglial subsets exist during the entire course of neurodegeneration, including the recovery phase, is currently unclear. Taking a single-cell RNA-sequencing approach in a susceptibility gene-free model of nerve injury, we identified a microglial subpopulation that ...[more]