Hypersensitivity to material and environmental burden as a possible cause of late complications of cardiac implantable electronic devices.

ABSTRACT:

Aims

To evaluate whether patients with late complications of pacemakers or implantable cardioverter-defibrillators have hypersensitivity reactions to some of the materials used in generators or in electrodes, or to environmental metal burden.

Methods and results

The cohort consisted of 20 men and 4 women (mean age: 62.3 ± 17.2 years) who had a history of late complications of implanted devices. The control group involved 25 men and 8 women (mean age: 64.6 ± 14.0 years) who had comparable devices, but no history of late complications. Lymphocyte transformation test was used to evaluate hypersensitivity to eight metal pollutants (antimony, manganese, mercury, molybdenum, nickel, platinum, tin, and titanium) selected by results of questionnaires on environmental burden, and by

SUBMITTER: Manousek J 

PROVIDER: S-EPMC6123938 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature