Ontology highlight
ABSTRACT:
SUBMITTER: Bernardo AS
PROVIDER: S-EPMC6124576 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Bernardo Andreia S AS Jouneau Alice A Marks Hendrik H Kensche Philip P Kobolak Julianna J Freude Kristine K Hall Vanessa V Feher Anita A Polgar Zsuzsanna Z Sartori Chiara C Bock Istvan I Louet Claire C Faial Tiago T Kerstens Hindrik H D HHD Bouissou Camille C Parsonage Gregory G Mashayekhi Kaveh K Smith James C JC Lazzari Giovanna G Hyttel Poul P Stunnenberg Hendrik G HG Huynen Martijn M Pedersen Roger A RA Dinnyes Andras A
Biology open 20180817 8
During early mammalian development, transient pools of pluripotent cells emerge that can be immortalised upon stem cell derivation. The pluripotent state, 'naïve' or 'primed', depends on the embryonic stage and derivation conditions used. Here we analyse the temporal gene expression patterns of mouse, cattle and porcine embryos at stages that harbour different types of pluripotent cells. We document conserved and divergent traits in gene expression, and identify predictor genes shared across the ...[more]