Ontology highlight
ABSTRACT:
SUBMITTER: Bak AM
PROVIDER: S-EPMC6124727 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Bak Ann Mosegaard AM Vendelbo Mikkel Holm MH Christensen Britt B Viggers Rikke R Bibby Bo Martin BM Rungby Jørgen J Jørgensen Jens Otto Lunde JOL Møller Niels N Jessen Niels N
PloS one 20180905 9
Insulin resistance is a well-known physiological adaptation to prolonged fasting in healthy skeletal muscle. Obesity is associated with insulin resistance and metabolic inflexibility in skeletal muscle, and a pronounced increase in the risk of metabolic complications. Under the hypothesis that the metabolic traits of insulin resistance associated with prolonged fasting are different from insulin resistance associated with obesity, we examined nine obese and nine lean participants during 12 and 7 ...[more]