Ontology highlight
ABSTRACT:
SUBMITTER: Park HH
PROVIDER: S-EPMC6125299 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Frontiers in immunology 20180830
Tumor necrosis factor receptor-associated factor (TRAF) proteins are key signaling molecules that function in various cellular signaling events including immune response, cell death and survival, development, and thrombosis. Their roles in cellular signaling are mediated mostly by direct interactions with various receptors via the TRAF domain. To determine how specific TRAF domains can interact with various receptors with a limited binding interface and how similar binding interfaces of TRAF fam ...[more]