Ontology highlight
ABSTRACT:
SUBMITTER: Ha SG
PROVIDER: S-EPMC6126992 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Ha Sung Gil SG Dileepan Mythili M Ge Xiao Na XN Kang Bit Na BN Greenberg Yana G YG Rao Amrita A Muralidhar Girija G Medina-Kauwe Lali L Thompson Michael A MA Pabelick Christina M CM O'Grady Scott M SM Rao Savita P SP Sriramarao P P
The Journal of allergy and clinical immunology 20180306 6
<h4>Background</h4>Altered epithelial physical and functional barrier properties along with T<sub>H</sub>1/T<sub>H</sub>2 immune dysregulation are features of allergic asthma. Regulation of junction proteins to improve barrier function of airway epithelial cells has the potential for alleviation of allergic airway inflammation.<h4>Objective</h4>We sought to determine the immunomodulatory effect of knob protein of the adenoviral capsid on allergic asthma and to investigate its mechanism of action ...[more]