Ontology highlight
ABSTRACT:
SUBMITTER: Sun Z
PROVIDER: S-EPMC6127252 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Sun Zhihao Z Shi Baolan B Meng Feifei F Ma Ruonan R Hu Qingyun Q Qin Tao T Chen Sujuan S Peng Daxin D Liu Xiufan X
Frontiers in microbiology 20180831
Both high- and low-pathogenic H7N9 influenza A virus (IAV) infections have been found in human and poultry in China, and most human cases are related to contact with infected poultry. It is necessary to develop a rapid and simple method to detect H7N9 IAV in poultry. In this study, 13 monoclonal antibodies (McAbs) against the H7N9 IAV hemagglutinin were developed, and three critical amino acid epitopes (198, 227, 235) were identified based on the reactivity of these variant and wild-type strains ...[more]